The Education Ministry said on Sunday that 130 schools and kindergartens have been closed due to staff and students contracting the virus in the past 10 days - 24 of them since Saturday.
Additionally, 17,605 students and staff members are now in quarantine, an increase of 1,282 since Saturday.
So far, 352 students and staff members nationwide have been diagnosed with the virus in the current wave, including 22 over the past 24 hours.
The Health Ministry also said that more people have tested positive for coronavirus in Tel Aviv than Jerusalem since Friday, with 46 new cases in the coastal city as opposed to 37 in the capital.
The ministry also reported that over the past five days, some 13,000 tests for the virus were conducted in Jerusalem, while at the same time, only about 3,600 were carried out in Tel Aviv.
According to the ministry's data, 111 new COVID-19 patients have been diagnosed, with the total number of cases rising to 17,863.
Three more patients have died from virus-related complications, bringing the total number of fatalities from the disease up to 298.
There has also been a climb in the number of people requiring respiratory assistance, with 23 patients currently using ventilators.
The number of daily recoveries has declined over the past few days, with only 26 registered on Sunday, while the number of active patients has risen by 283 to 2,474.
Health officials said Sunday that they fear a new outbreak is taking place in Jaffa, where 10 people have so far been diagnosed with the virus in recent days.